{"id":20183,"date":"2026-04-22T11:20:09","date_gmt":"2026-04-22T09:20:09","guid":{"rendered":"https:\/\/www.bio-sistemak.eus\/2025111088-2\/"},"modified":"2026-04-22T11:38:34","modified_gmt":"2026-04-22T09:38:34","slug":"2025111088-2","status":"publish","type":"page","link":"https:\/\/www.bio-sistemak.eus\/en\/2025111088-2\/","title":{"rendered":"2025111088"},"content":{"rendered":"

SepsisIA: Implementation and external validation of an innovative AI-based early warning system for sepsis<\/h2>
\n

\"\"<\/a>Project call:<\/strong> <\/span>Grants for Health Research and Development Projects. Basque Government Department of Health. Call 2025<\/p>\n

Funding body:<\/strong><\/span> Department of Health, Basque Government<\/p>\n

File number:<\/strong><\/span> 2025111088<\/p>\n

Principal Investigator: <\/strong><\/span> Urko Aguirre Larrakoetxea<\/p>\n

Funding awarded: <\/strong><\/span>\u20ac61,261.24<\/p>\n

Description: <\/strong><\/span>To develop and implement an advanced research and clinical support infrastructure based on artificial intelligence for the early detection and management of sepsis in the emergency departments of the Basque Health System, using real-time electronic health record data, integrated into Osakidetza\u2019s care protocols and aimed at improving clinical outcomes, reducing complications and optimising healthcare organisation in accordance with the principles of responsible AI.<\/p>\n

Objetive:<\/strong><\/span>
\n1.- Desarrollar un sistema estructurado de rean\u00e1lisis gen\u00e9tico para mejorar el diagn\u00f3stico temprano y preciso de las enfermedades raras, abordando la interpretaci\u00f3n de variantes de significado incierto.
\n2.- Integrar datos gen\u00e9ticos y cl\u00ednicos fenot\u00edpicos, junto con pruebas funcionales y otras evidencias complementarias, para aumentar la robustez y fiabilidad de la interpretaci\u00f3n diagn\u00f3stica.
\n3.- Reducir la incertidumbre cl\u00ednica y mejorar la toma de decisiones, el asesoramiento gen\u00e9tico y la calidad asistencial mediante la aplicaci\u00f3n del rean\u00e1lisis en casos reales.
\n4.- Establecer un proceso continuo y sostenible de actualizaci\u00f3n diagn\u00f3stica, alineado con los circuitos asistenciales y con los principios \u00e9ticos y regulatorios del Sistema Vasco de Salud.<\/p>\n

Expected results:
\n<\/strong><\/span>– Development and validation of an AI-based early warning system for the early diagnosis and clinical management of sepsis, integrated into clinical practice and Osakidetza\u2019s electronic health records.
\n– Improvement in patient health and safety through early detection, reduction in morbidity and mortality, readmissions and prolonged ICU stays, as well as the optimisation of resources in A&E, laboratory and intensive care.
\n– Generation of transferable scientific results, with publications in international journals, open-access dissemination and potential exploitation of the predictive models and digital solutions developed.
\n– Contribution to the development of an innovative, scalable service aligned with the principles of responsible AI, with a positive organisational and economic impact on the Basque Health System.
\n– Strengthening of the Basque innovation system through interdisciplinary collaboration and the international positioning of the Basque Country in artificial intelligence applied to sepsis and critical care.
\n<\/span><\/p>\n<\/div>

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